I just can’t believe that someone in political office can say something like this and believe that it could actually do anything than turn any civilised people against them, regardless of their religion (or lack of it), should they carry out the threat.

To quote the ABC News report:

In a radio interview last week about Muslims and the war on terror, Mr Tancredo said US bombs could “take out their holy sites”.
When asked if he was “talking about bombing Mecca,” Mr Tancredo reportedly replied, “Yeah.”

I don’t really know what to say about that, it demonstrates an appalling lack of understanding of what’s actually going on, and how what he said could be used against the people he purports to represent (not to mention their allies).